Building a
brighter future.

IDefine is committed to identifying life-changing treatments & cures for those with Kleefstra syndrome (KS), a neurodevelopmental disorder caused by a loss of function in one copy of the gene EHMT1.

To learn more about IDefine’s current efforts, please read this update of our Foundation Highlights!

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Hezekiah’s Journey: A Story of Love, Advocacy, and Strength
By Kiante and Marlon Holmes I remember the day like it was yesterday, although it was eight years ago. It was just a regular afternoon, and I had gone...

IDefine is a nonprofit organization that exists to provide a central community for families affected by Kleefstra Syndrome (KS)

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If you have any questions feel free to contact us. We will be sure to get back to you as soon as possible.